Article
Modulation of estrogen receptor alpha activity and expression during breast cancer progression.
Vitamins and hormones - 1 Jan 2013
Kerdivel Gwenneg, Flouriot Gilles, Pakdel Farzad
Abstract excerpt
Seventy percent of breast tumors express the estrogen receptor (ER), which is generally considered to predict a better outcome relative to ER-negative tumors, as they often respond to antiestrogen therapies. During cancer progression, mammary tumors can escape from estrogen control, resulting in the acquisition of invasive properties and resistance to treatment. ER expression is a dynamic phenomenon and is finely...
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