Article

Characterizing novel molecular mechanisms involved in breast cancer tumourigenesis/progression and tamoxifen resistance

2016-01-01

Abstract excerpt

Breast cancer is the most common cancer among women. Breast cancer tumorigenesis could be due to loss/mutation of BRCA1, yet the mechanisms underlying BRCA1-associated tumorigenesis are not well understood. Tamxoifen stands in the first-line for treatment of oestrogen receptor (ER) positive breast cancers but drug resistance significantly compromises its clinical efficacy in preventing cancer progression and impro...

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Literature Corpus work: 1cafd24e-f3ad-5877-8281-ea045fb822c5
DOI: 10.25560/69786

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