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Article

STAT 1 facilitates oestrogen receptor α transcription and stimulates breast cancer cell proliferation

17 Oct 2018

Abstract excerpt

Oestrogen receptor α (ERα) is overexpressed in two-thirds of all breast cancer cases and is involved in breast cancer development and progression. Although ERα -positive breast cancer can be effectively treated by endocrine therapy, endocrine resistance is an urgent clinical problem. Thus, further understanding of the underlying mechanisms involved in ERα signalling is critical in dealing with endocrine...

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Share to Cytokine Signaling Pathways and Interactions
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PMID: 30334368
DOI: 10.1111/jcmm.13882

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