Article

Alzheimer’s disease causes bone marrow myelopoiesis dysfunction

2025-10-07

Abstract excerpt

Accumulating evidence suggests that both innate and adaptive immunity play crucial roles in combating Alzheimer’s disease (AD). Specifically, enhancing the homing of monocyte-derived macrophages to the affected brain has been shown to reduce local inflammation, decrease proteinopathy, rescue neurons, and mitigate cognitive decline. However, the factors limiting their spontaneous recruitment remain unclear. Using m...

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Literature Corpus work: 97b8e1f1-4a4f-5c38-9989-b76755f03fd3
DOI: 10.1101/2025.10.06.680030

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