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Cellular transcriptional alterations of peripheral blood in Alzheimer’s disease

29 Aug 2022

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD), a progressive neurodegenerative disease, is the most common cause of dementia worldwide. Accumulating data support the contributions of the peripheral immune system in AD pathogenesis. However, there is a lack of comprehensive understanding about the molecular characteristics of peripheral immune cells in AD. METHODS: To explore the alterations of cellular composition and the...

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PMID: 36031604
DOI: 10.1186/s12916-022-02472-4

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