Article

Tracking the progression of Alzheimer’s disease with peripheral blood monocytes

2023-03-01

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease (AD) is the most common form of dementia with the symptoms gradually worsening over the years. However, the driving pathological processes occur well before the appearance of symptoms. AD patients display signs of systemic inflammation, suggesting that it could precede the well-established AD hallmarks. We recently showed that the innate immune response in the form of monoc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: aca79834-90e1-5aba-9659-1bbbe9f8423a
DOI: 10.1101/2023.02.28.530459

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Tracking the progression of Alzheimer’s disease with peripheral blood monocytesDOI 10.1101/2023.02.28.530459Read

Single-cell multi-omic profiling allows the dissection of peripheral immune phenotypes in Alzheimer’s Disease progressionSemantic proximity Read

Human peripheral monocytes capture elements of the state of microglial activation in the brainSemantic proximity Read

Systems-level analysis of peripheral blood gene expression in dementia patients reveals an innate immune response shared across multiple disordersSemantic proximity Read

Identification of immune cells infiltrating in hippocampus and key genes associated with Alzheimer’s diseaseSemantic proximity Read

The role of monocytes and macrophages in the progression of Alzheimer’s diseaseSemantic proximity Read

Analysis of Blood Gene Expression Data Toward Early Detection of Alzheimer’s DiseaseSemantic proximity Read

Alzheimer's Disease Blood Biomarkers Associated With Neuroinflammation as Therapeutic Targets for Early Personalized InterventionSemantic proximity Read

Key inflammatory pathway activations in the MCI stage of Alzheimer’s diseaseSemantic proximity Read

Cellular transcriptional alterations of peripheral blood in Alzheimer’s diseaseSemantic proximity Read

Integrating peripheral blood and brain transcriptomics to identify immunological features associated with Alzheimer’s disease in mild cognitive impairment patientsSemantic proximity Read

Discovery and Validation of Key Biomarkers Based on Immune Infiltrates in Alzheimer’s DiseaseSemantic proximity Read

Identification of novel risk genes for Alzheimer's disease by integrating genetics from hippocampus.Semantic proximity Read