Article

Alzheimer’s patient brain myeloid cells exhibit enhanced aging and unique transcriptional activation

2019-04-19

Abstract excerpt

Gene expression changes in brain microglia from mouse models of Alzheimer’s disease (AD) are highly characterized and reflect specific myeloid cell activation states that could modulate AD risk or progression. While some groups have produced valuable expression profiles for human brain cells 1–4 , the cellular clarity with which we now view transcriptional responses in mouse AD models has not yet been realized fo...

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Literature Corpus work: db0b48e3-c704-5910-a808-2935c020ae0f
DOI: 10.1101/610345

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