Article

Two-phase sample selection strategies for design and analysis in post-genome wide association fine-mapping studies

2021-05-18

Abstract excerpt

Post-GWAS analysis, in many cases, focuses on fine-mapping targeted genetic regions discovered at GWAS-stage; that is, the aim is to pinpoint potential causal variants and susceptibility genes for complex traits and disease outcomes using next-generation sequencing (NGS) technologies. Large-scale GWAS cohorts are necessary to identify target regions given the typically modest genetic effect sizes. In this context,...

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Literature Corpus work: 979d2503-5aad-5b8c-bcc7-55a0b6d4bab3
DOI: 10.1101/2021.05.15.21257266

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