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Article

Optimal two-stage genotyping designs for genome-wide association scans.

Genetic epidemiology - 1 May 2006

Wang Hansong, Thomas Duncan C, Pe'er Itsik, Stram Daniel O

Abstract excerpt

The much-anticipated fixed-array, genome-wide SNP genotyping technologies make large-scale genome-wide association scans now possible for large numbers of subjects. In this paper we reconsider the problem (Satagopan and Elston [2003] Genet Epidemiol 25:149-157) of optimizing a two-stage genotyping design to deal with important new issues that are relevant when studies are expanded from candidate gene size to a...

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PMID: 16607626
DOI: 10.1002/gepi.20150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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