Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two-phase stratified sampling designs for regional sequencing.

Genetic epidemiology - 1 May 2012

Chen Zhijian, Craiu Radu V, Bull Shelley B

Abstract excerpt

By systematic examination of common tag single-nucleotide polymorphisms (SNPs) across the genome, the genome-wide association study (GWAS) has proven to be a successful approach to identify genetic variants that are associated with complex diseases and traits. Although the per base pair cost of sequencing has dropped dramatically with the advent of the next-generation technologies, it may still only be feasible...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Computational Biology
Share to Computer Simulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to Models, Statistical

Share to Molecular Epidemiology

Share to Probability

Share to Regression Analysis

Source

Identifiers

PMID: 22460746
DOI: 10.1002/gepi.21624

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two-phase stratified sampling designs for regional sequencing.PMID 22460746Read ↗

Two-phase designs to follow-up genome-wide association signals with DNA resequencing studies.Semantic proximity Read ↗

Two-phase sample selection strategies for design and analysis in post-genome wide association fine-mapping studiesSemantic proximity Read ↗

Two-Stage sampling designs for gene association studies.Semantic proximity Read ↗

Two-phase sample selection strategies for design and analysis in post-genome-wide association fine-mapping studies.Semantic proximity Read ↗

Optimal designs for two-stage genome-wide association studies.Semantic proximity Read ↗

Two-phase designs for joint quantitative-trait-dependent and genotype-dependent sampling in post-GWAS regional sequencing.Semantic proximity Read ↗

Probability that a two-stage genome-wide association study will detect a disease-associated snp and implications for multistage designs.Semantic proximity Read ↗

Optimal DNA pooling-based two-stage designs in case-control association studies.Semantic proximity Read ↗

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies.Semantic proximity Read ↗

Multistage sampling for genetic studies.Semantic proximity Read ↗

Including sampling and phenotyping costs into the optimization of two stage designs for genomewide association studies.Semantic proximity Read ↗

A note on the efficiencies of sampling strategies in two-stage Bayesian regional fine mapping of a quantitative trait.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.