Article

Mapping Intrapatient Response Heterogeneity and Lesion-specific Relapse Dynamics in Metastatic Colorectal Cancer

2022-03-28

Abstract excerpt

<title>Abstract</title> <p>Achieving systemic tumor control across metastases is vital for long-term patient survival but remains intractable in many patients. High intrapatient heterogeneity persists, conferring many dissociated responses across metastatic lesions. Most studies of metastatic disease focus on tumor molecular and cellular features, which are crucial to elucidating the mechanisms underlying intrapa...

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Literature Corpus work: 97777a1e-b126-5e0d-9676-9c4a892bace7
DOI: 10.21203/rs.3.rs-1447896/v1

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