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Spatial transcriptomic revealed intratumor heterogeneity and cancer stem cell enrichment in colorectal cancer metastasis

2022-03-08

Abstract excerpt

<h4>Background: </h4> & Aims Metastasis is the main cause of mortality in colorectal cancer (CRC) patients. Exploring the mechanisms of metastasis is of great importance in both clinical and fundamental CRC research. CRC is a highly heterogeneous disease with variable therapeutic outcomes of treatment. Approach & Results In this study, we applied spatial transcriptomics (ST) to generate a tissue-wide transcriptome...

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Literature Corpus work
bc8b5583-d59f-506a-b5a5-241d63480ac7
DOI
10.21203/rs.3.rs-1403953/v1
Open publication

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Spatial transcriptomic revealed intratumor heterogeneity and cancer stem cell enrichment in colorectal cancer metastasisDOI 10.21203/rs.3.rs-1403953/v1
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