Article

Heterogenous Profiles Between Matched Primary Tumors and Brain Metastases Reveal Tumor Evolution

2021-11-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Brain metastases (BMs) are the most common central nervous system (CNS) malignant tumors, with rapid disease progression and extremely poor prognosis. The heterogeneity between primary tumors and BMs leads to the divergent efficacy of the adjuvant therapy response to primary tumors and BMs. However, the extent of heterogeneity between primary tumors and BMs, and...

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Literature Corpus work: 1cebb25a-c235-5416-8fc7-314b752d4075
DOI: 10.21203/rs.3.rs-1105667/v1

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