Article

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

2024-01-15

Abstract excerpt

Deciphering the structural variation across tumour genomes is crucial to determine the events driving tumour progression and better understand tumour adaptation and evolution. High grade serous ovarian cancer (HGSOC) is an exemplar tumour type showing extreme, but poorly characterised structural diversity. We comprehensively describe the mutational landscape driving HGSOC, exploiting a large (N=324), deeply whole...

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Literature Corpus work: 9739a366-3e6c-592e-980d-2f0947d4f694
DOI: 10.1101/2024.01.12.575376

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