Article

Seasonal influenza viruses show distinct adaptive dynamics during growth in chicken eggs

2025-06-17

Abstract excerpt

Human influenza viruses are grown in chicken eggs for vaccine production. Sequences of these egg-passaged viruses give us the opportunity to examine the evolution that occurs when these human viruses are subjected to the selective pressure of growing in chicken eggs, which (among other things) express different sialic acid receptors. The repetition of this evolutionary experiment in hundreds of strains over the pa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 972f7c08-cb0b-58cb-ac09-78d57b94c36f
DOI: 10.1101/2025.06.12.659400

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Seasonal influenza viruses show distinct adaptive dynamics during growth in chicken eggsDOI 10.1101/2025.06.12.659400Read

Seasonal Influenza Viruses Show Distinct Adaptive Dynamics During Growth in Chicken Eggs.Semantic proximity Read

Natural selection on the influenza virus genome.Semantic proximity Read

Molecular changes associated with adaptation of human influenza A virus in embryonated chicken eggs.Semantic proximity Read

Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution.Semantic proximity Read

Passage Adaptation Correlates With the Reduced Efficacy of the Influenza VaccineSemantic proximity Read

Rationally Designed Influenza Virus Vaccines That Are Antigenically Stable during Growth in Eggs.Semantic proximity Read

Exploring variation in the d(N)/d(S) ratio among sites and lineages using mutational mappings: applications to the influenza virus.Semantic proximity Read

Egg-adaptation pathway of human influenza H3N2 virus is contingent on natural evolutionSemantic proximity Read

Mutations of novel influenza A(H10N8) virus in chicken eggs and MDCK cells.Semantic proximity Read

Mutational pattern of influenza B viruses adapted to high growth replication in embryonated eggs.Semantic proximity Read

Egg fluids and cells of the chorioallantoic membrane of embryonated chicken eggs can select different variants of influenza A (H3N2) viruses.Semantic proximity Read

Generation of Live Attenuated Influenza Virus by Using Codon Usage BiasSemantic proximity Read