Article

Compensatory Mutations in Avian Influenza H7N1 Hemagglutinin Drive Avian Host Adaptation and Antigenic Drift without Enhancing Replication in Human Cells

2026-09-01

Abstract excerpt

<title>Abstract</title> <p>Avian influenza A viruses (AIVs) of the H7 subtype have caused outbreaks in poultry and human ranging from mild to fatal disease. In Europe, H7 viruses have demonstrated an unusual capacity for prolonged circulation in poultry, most notably during the Italian H7N1 epizootic (1999–2001), which persisted despite control measures and provides a model to study viral adaptation under sustain...

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Literature Corpus work: 46d962d4-2009-513c-89d0-dfb02f18462b
DOI: 10.21203/rs.3.rs-10351951/v1

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Compensatory Mutations in Avian Influenza H7N1 Hemagglutinin Drive Avian Host Adaptation and Antigenic Drift without Enhancing Replication in Human CellsDOI 10.21203/rs.3.rs-10351951/v1Read

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