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Article

Mutational pattern of influenza B viruses adapted to high growth replication in embryonated eggs.

Virus research - 1 May 2005

Lugovtsev Vladimir Y, Vodeiko Galina M, Levandowski Roland A

Abstract excerpt

Improved replication of influenza viruses in embryonated chicken eggs (CE) permits increased vaccine production and availability. We investigated the growth properties of influenza B viruses in relation to specific mutations occurring after serial passage in CE. In serial passage experiments yielding high growth variants of B/Victoria/504/2000, mutations predicted to alter amino acid (AA) composition occurred...

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Identifiers

PMID: 15763145
DOI: 10.1016/j.virusres.2004.11.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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