Article

Computational enhancement of single-cell sequences for inferring tumor evolution

2018-06-07

Abstract excerpt

Motivation : Tumor sequencing has entered an exciting phase with the advent of single-cell techniques that are revolutionizing the assessment of single nucleotide variation (SNV) at the highest cellular resolution. However, state-of-the-art single-cell sequencing technologies produce data with many missing bases (MBs) and incorrect base designations that lead to false-positive (FP) and false-negative (FN) detectio...

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Literature Corpus work: f106827d-d9ae-5bed-890c-95f5949c323c
DOI: 10.1101/341743

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