Article

Hippo signalling regulates the nuclear behaviour and DNA dwell times of YAP and TEAD to control transcription

2025-03-13

Abstract excerpt

<h4>ABSTRACT</h4> Over the past two decades, genetic and proteomic screens have enabled the discovery and elucidation of the Hippo pathway as a complex signalling network that controls tissue growth and cell fate and which is of major importance for human cancers. Despite these advances, our understanding of how Hippo signalling regulates transcription is less clear. To address this, we used live microscopy appro...

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Literature Corpus work: 970e882f-9ed1-5dab-82c5-48642ebc2a88
DOI: 10.1101/2025.03.11.642705

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