Article

Multiomic profiling of a unique in-transit melanoma cohort identifies melanoma differentiation as predictor of tumor progression and therapy response

2025-10-02

Abstract excerpt

<h4>ABSTRACT</h4> Melanoma patients with in-transit metastasis (ITM), a stage of disease where melanoma has metastasized to sites in between the primary lesion and draining lymph node, vary significantly in their clinical outcomes, but the biology driving differential outcomes in ITM is poorly understood. To elucidate the mechanisms of differential outcomes, we utilized multimodal molecular profiling (WES, RNA-se...

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Literature Corpus work: 96f92a91-ac1a-55ab-9f68-806b54902ac6
DOI: 10.1101/2025.10.01.679282

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