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Kidney-specific methylation patterns correlate with kidney function and are lost upon kidney disease progression

2022-09-19

Abstract excerpt

Chronological and biological age correlate with DNA methylation levels at specific sites in the genome. Linear combinations of multiple methylation sites, termed epigenetic clocks, can inform us of the chronological age and predict multiple health-related outcomes. However, why some sites correlate with lifespan, healthspan, or specific medical conditions remains poorly understood. Kidney fibrosis is the common pa...

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Identifiers and source

Literature Corpus work
96daa7bc-9168-5fa6-9d0b-9432cf885329
DOI
10.1101/2022.09.19.508466
Open publication

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Kidney-specific methylation patterns correlate with kidney function and are lost upon kidney disease progressionDOI 10.1101/2022.09.19.508466
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