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Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development

7 Oct 2013

Abstract excerpt

BACKGROUND: One in eleven people is affected by chronic kidney disease, a condition characterized by kidney fibrosis and progressive loss of kidney function. Epidemiological studies indicate that adverse intrauterine and postnatal environments have a long-lasting role in chronic kidney disease development. Epigenetic information represents a plausible carrier for mediating this programming effect. Here we...

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PMID: 24098934
DOI: 10.1186/gb-2013-14-10-r108

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