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The Emerging Role of DNA Methylation in Kidney Transplantation: A Perspective

18 Jan 2016

Abstract excerpt

Allograft outcome depends on a range of factors, including donor age, the allo-immune response, ischemia-reperfusion injury, and interstitial fibrosis of the allograft. Changes in the epigenome, and in DNA methylation in particular, have been implicated in each of these processes, in either the kidney or other organ systems. This review provides a primer for DNA methylation analyses and a discussion of the...

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PMID: 26780242
DOI: 10.1111/ajt.13585

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