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Genome-wide DNA methylation analysis revealed epigenetic mechanism underlying end stage renal disease

2025-07-21

Abstract excerpt

End-stage renal disease (ESRD) remains to be a major clinical challenge with persistently high morbidity and mortality, and its molecular mechanisms, particularly those shared among diverse primary kidney diseases during the progression to ESRD, have not been studied. Here we conducted a large-scale two-stage epigenome-wide association study of ESRD in two independent cohorts consisting of 704 controls and 1031 ES...

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Literature Corpus work
6d3eae99-1c46-573e-85ab-aadbb01d88c7
DOI
10.1101/2025.07.20.25331626
Open publication

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Genome-wide DNA methylation analysis revealed epigenetic mechanism underlying end stage renal diseaseDOI 10.1101/2025.07.20.25331626
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