Article

Heart Disease in a Mutant Mouse Model of Spontaneous Eosinophilic Myocarditis Maps to Three Highly Significant Loci

2019-08-28

Abstract excerpt

<h4>Background</h4> Heart disease (HD) is the major cause of morbidity and mortality in patients with hypereosinophilic diseases. Due to a lack of adequate animal models, our understanding of the pathophysiology of eosinophil-mediated diseases with heart complications is limited. We have discovered a mouse mutant, now maintained on an A/J inbred background, that spontaneously develops hypereosinophilia in multipl...

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Literature Corpus work: 96d608ec-81a7-5c81-a01a-98a948cf71ad
DOI: 10.1101/747519

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