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Article

Heart disease in a mutant mouse model of spontaneous eosinophilic myocarditis maps to three loci.

BMC genomics - 11 Oct 2019

Zimmermann Nives, Gibbons William J, Homan Shelli M, Prows Daniel R

Abstract excerpt

BACKGROUND: Heart disease (HD) is the major cause of morbidity and mortality in patients with hypereosinophilic diseases. Due to a lack of adequate animal models, our understanding of the pathophysiology of eosinophil-mediated diseases with heart complications is limited. We have discovered a mouse mutant, now maintained on an A/J inbred background, that spontaneously develops hypereosinophilia in multiple...

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Identifiers

PMID: 31601172
DOI: 10.1186/s12864-019-6108-0
PMCID: PMC6788080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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