Article
Complex genetic control of host susceptibility to coxsackievirus B3-induced myocarditis.
Genes and immunity - 1 Apr 2007
Aly M, Wiltshire S, Chahrour G, Osti J-C Loredo, Vidal S M
Abstract excerpt
The pathogenesis of viral myocarditis is a multifactorial process involving host genetics, viral genetics and the environment in which they interact. We have used a model of infection with coxsackievirus B3 (CVB3) to characterize the contribution of host genetics to viral myocarditis in mice of different genetic backgrounds but with a common H2 haplotype: A/J and B10.A-H2(a). Here we have used Evans blue dye as a...
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