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Article

Pathophysiology of hypereosinophilia-associated heart disease

2024-07-05

Abstract excerpt

<h4>Background</h4> Cardiac complications in patients with hypereosinophilia cause significant morbidity and mortality. However, mechanisms of how eosinophilic inflammation causes heart damage are poorly understood. <h4>Methods</h4> We developed a model of hypereosinophilia-associated heart disease by challenging hypereosinophilic mice with peptide from the cardiac myosin heavy chain. Disease outcomes were measu...

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Literature Corpus work
a77316fe-9185-510c-9dda-b4911ba2231b
DOI
10.1101/2024.07.03.601845
Open publication

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Pathophysiology of hypereosinophilia-associated heart diseaseDOI 10.1101/2024.07.03.601845
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