Article

Hypereosinophilia causes progressive cardiac pathologies in mice

2022-05-05

Abstract excerpt

Hypereosinophilic syndrome is a progressive disease with extensive eosinophilia that results in organ damage. Cardiac pathologies are the main reason for its high mortality rate. A better understanding of the mechanisms of eosinophil-mediated tissue damage would benefit therapeutic development. Here, we describe the cardiac pathologies that developed in a mouse model of hypereosinophilic syndrome. These IL-5 trans...

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Literature Corpus work: 6aad145e-cd83-5edb-8160-9c4e37ede6dd
DOI: 10.1101/2022.05.04.490445

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