Article

The effects of conditional loss of myosin binding protein H-like on cardiac function

2024-10-11

Abstract excerpt

<h4>ABSTRACT</h4> Mutations in the myosin-binding protein H-like (MyBP-HL) gene, MYBPHL , are linked to hereditary dilated cardiomyopathy (DCM), atrial fibrillation, and atrioventricular arrhythmias. MyBP-HL is a sarcomeric protein that is highly expressed in the atria with only scarce, distinct clusters of MyBP-HL positive cells within and surrounding the ventricular conduction system. Constitutive knock-out of...

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Literature Corpus work: 5221bf75-6578-5311-93cf-1e0935e593d8
DOI: 10.1101/2024.10.07.617136

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