Article

Metformin Prevents Oxidative Stress-Induced Premature Senescence in Astrocyte Cells

2025-02-05

Abstract excerpt

Metformin, an antidiabetic drug, has been shown to exert neuroprotective, antioxidant and anti-inflammatory properties. Senescent astrocytes have been shown to accumulate with age and in the context of many neurodegenerative diseases. The present study investigated the effects of metformin on the oxidative stress-induced premature senescence in astrocyte cells. For this purpose, primary culture astrocyte cells wer...

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Literature Corpus work: 965c4e51-53cf-5831-8eb9-897bc71f92c5
DOI: 10.22541/au.173875324.47590402/v1

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