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Article

Doxorubicin Induces a Senescent Phenotype in Murine and Human Astrocytes

1 Aug 2025

Abstract excerpt

ABSTRACT Aging is a complex biological process that significantly impacts the central nervous system (CNS). Astrocytes, critical support cells in the brain, undergo senescence with age, contributing to neurodegenerative diseases. While previous studies have utilized murine models to investigate astrocyte senescence, human astrocytes offer a more physiologically relevant system to study age‐related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40762103
DOI: 10.1111/jnc.70177

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