Article

Senescent Phenotype of Astrocytes Leads to Microglia Activation and Neuronal Death

2021-12-29

Abstract excerpt

<title>Abstract</title> <p>Astrocyte, the most abundant cell type in the central nervous system, is increasingly recognized and is thought to depend on curial and diverse roles in maintaining brain homeostasis, the blood-brain barrier, ion homeostasis, secrete neurotrophic factors and regulate synaptic transmission which is essential to tune individual-to-network neuronal activity. Senescence in astrocytes has be...

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Literature Corpus work: 538956a7-e8d0-5db3-ba14-60e609a382bf
DOI: 10.21203/rs.3.rs-1186816/v1

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