Article

Genetic background influences the 5XFAD Alzheimer’s disease mouse model brain proteome

2023-06-13

Abstract excerpt

There is a pressing need to improve the translational validity of Alzheimer’s disease (AD) mouse models. Introducing genetic background diversity in AD mouse models has been proposed as a way to increase validity and enable discovery of previously uncharacterized genetic contributions to AD susceptibility or resilience. However, the extent to which genetic background influences the mouse brain proteome and its per...

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Identifiers and source

Literature Corpus work: 9603aaeb-39fb-5d9e-8097-8a10c74f646f
DOI: 10.1101/2023.06.12.544646

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