Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and environmental modifiers of Alzheimer's disease phenotypes in the mouse.

Current Alzheimer research - 1 Dec 2006

Ryman Davis, Lamb Bruce T

Abstract excerpt

As a group, strains of laboratory mice carrying Alzheimer's disease (AD)-related transgenes are currently the most widely studied animal models of AD. Many AD mouse models carrying the same or similar transgene constructs demonstrate strikingly different phenotypic responses to transgene expression, mimicking the apparent genetic complexity of AD pathogenesis seen in the human population. Genetic differences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Peptides
Share to Amyloid beta-Protein Precursor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Environment

Share to Phosphorylation

Share to Piperidines

Share to Pyridines

Share to tau Proteins

Source

Identifiers

PMID: 17168645
DOI: 10.2174/156720506779025198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and environmental modifiers of Alzheimer's disease phenotypes in the mouse.PMID 17168645Read ↗

Practical considerations for choosing a mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

Toward more predictive genetic mouse models of Alzheimer's diseaseSemantic proximity Read ↗

Updates on mouse models of Alzheimer’s diseaseSemantic proximity Read ↗

Gene-Environment Interaction Research and Transgenic Mouse Models of Alzheimer's DiseaseSemantic proximity Read ↗

Alzheimer's disease pathology in APOE transgenic mouse models: The Who, What, When, Where, Why, and How.Semantic proximity Read ↗

Transgenic mouse models of Alzheimer's disease: phenotype and application.Semantic proximity Read ↗

Relevance of Transgenic Mouse Models to Human Alzheimer DiseaseSemantic proximity Read ↗

APOEe4.Trem2*R47H Mice Show Changes in Alzheimer’s Disease-Relevant Processes in the Absence of Amyloid PlaquesSemantic proximity Read ↗

Transgenic Mouse Models of Alzheimer’s Disease: An Integrative AnalysisSemantic proximity Read ↗

Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease.Semantic proximity Read ↗

Genetic background regulates beta-amyloid precursor protein processing and beta-amyloid deposition in the mouse.Semantic proximity Read ↗

Alzheimer's disease: genetic studies and transgenic models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.