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Article

Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer’s Disease

6 Aug 2022

Abstract excerpt

Mouse models of Alzheimer's disease (AD) show progression through stages reflective of human pathology. Proteomics identification of temporal and sex-linked factors driving AD-related pathways can be used to dissect initiating and propagating events of AD stages to develop biomarkers or design interventions. In the present study, we conducted label-free proteome measurements of mouse hippocampus tissue with...

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PMID: 35944844
DOI: 10.1016/j.mcpro.2022.100280

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