Article

Genetic Characterization of HIV-1 tat Gene from Virologically Controlled HIV-infected Older Patients on Long-term Antiretroviral Therapy

2023-10-02

Abstract excerpt

Despite advancements in antiretroviral therapy (ART) that reduces the viral load to undetectable levels, viral eradication has not been achieved due to HIV-1 persistence in resting CD4+ T-cells. We, therefore, characterized the tat gene, which is essential for HIV-1 replication, from 20 viro-logically controlled HIV-infected (HIV+) older patients on long-term ART with improved CD4+ T-cell counts. PBMC genomic DNA...

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Literature Corpus work: 95e12105-a7d2-5006-b750-62390e388040
DOI: 10.20944/preprints202310.0046.v1

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