Article
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.
Nature - 21 Sept 2000
Allen T M, O'Connor D H, Jing P, Dzuris J L, Mothé B R, Vogel T U, Dunphy E, Liebl M E, Emerson C, Wilson N, Kunstman K J, Wang X, Allison D B, Hughes A L, Desrosiers R C, Altman J D, Wolinsky S M, Sette A, Watkins D I
Abstract excerpt
Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections are characterized by early peaks of viraemia that decline as strong cellular immune responses develop. Although it has been shown that virus-specific CD8-positive cytotoxic T lymphocytes (CTLs) exert selective p...
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