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Article

LTR and tat variability of HIV-1 isolates from patients with divergent rates of disease progression.

Virus research - 1 Sept 1998

Quiñones-Mateu M E, Mas A, Lain de Lera T, Soriano V, Alcamí J, Lederman M M, Domingo E

Abstract excerpt

The genetic heterogeneity and transcription activity of the human immunodeficiency virus type 1 (HIV-1) LTR region and tat gene have been examined. Comparison involved the relevant genomic regions of viruses isolated from twenty long-term survivors and from ten typical progressors. No significant differences were observed in mutation frequencies among the two groups, although there was a significant higher...

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PMID: 9833881
DOI: 10.1016/s0168-1702(98)00082-3

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