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Article

High-resolution structure of an HIV-1 quasispecies: identification of novel coding sequences.

AIDS (London, England) - 1 Oct 1992

Vartanian J P, Meyerhans A, Henry M, Wain-Hobson S

Abstract excerpt

OBJECTIVE: To characterize an HIV-1 quasispecies in vivo at high resolution (1%) in order to determine its genetic structure. METHODS: The first coding exon of tat was amplified by polymerase chain reaction from uncultured peripheral blood mononuclear cells of an HIV-1-infected patient. The products were cloned into M13mp18 RF, and 106 clones were sequenced. RESULTS: Thirty-one different Tat protein variants were...

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Identifiers

PMID: 1466840
DOI: 10.1097/00002030-199210000-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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