High-resolution structure of an HIV-1 quasispecies: identification of novel coding sequences.

doi:10.1097/00002030-199210000-00005

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Article

High-resolution structure of an HIV-1 quasispecies: identification of novel coding sequences.

AIDS (London, England) - 1 Oct 1992

Vartanian J P, Meyerhans A, Henry M, Wain-Hobson S

Abstract excerpt

OBJECTIVE: To characterize an HIV-1 quasispecies in vivo at high resolution (1%) in order to determine its genetic structure. METHODS: The first coding exon of tat was amplified by polymerase chain reaction from uncultured peripheral blood mononuclear cells of an HIV-1-infected patient. The produ...

Topics

Amino Acid Sequence
Bacteriophage M13
Cloning, Molecular
Exons
Genes, tat
Genes, vpu
Genetic Variation
HIV-1
Leukocytes, Mononuclear
Molecular Sequence Data
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