Article

Generation of a novel constitutive smooth muscle cell-specific <i>Myh11</i> -driven Cre mouse model

2024-11-09

Abstract excerpt

Dysfunction in either embryonic or postnatal vascular smooth muscle cells (SMCs) significantly contributes to the progression of various cardiovascular diseases. Therefore, elucidating the molecular mechanisms governing VSMC development and homeostasis is crucial. MYH11 is the most reliable lineage gene for SMCs and has been utilized to develop tamoxifen-inducible Cre driver lines for achieving SMC-specific gene...

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Literature Corpus work: 956de56b-4545-563a-81ab-431a1753efbf
DOI: 10.1101/2024.11.08.622724

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