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Article

Use of iPSC-Derived Smooth Muscle Cells to Model Physiology and Pathology.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2024

Kwartler Callie S, Esparza Pinelo Jose Emiliano

Abstract excerpt

The implementation of human induced pluripotent stem cell (hiPSC) models has introduced an additional tool for identifying molecular mechanisms of disease that complement animal models. Patient-derived or CRISPR/Cas9-edited induced pluripotent stem cells differentiated into smooth muscle cells (SMCs) have been leveraged to discover novel mechanisms, screen potential therapeutic strategies, and model in vivo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Smooth, Vascular

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Source

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Identifiers

PMID: 38695171
DOI: 10.1161/ATVBAHA.123.319703
PMCID: PMC11209779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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