Article

Cockayne Syndrome B protein selectively interacts and resolves intermolecular DNA G-quadruplex structures

2021-03-25

Abstract excerpt

Guanine-rich DNA can fold into secondary structures known as G-quadruplexes (G4s). G4s can form from a single DNA-strand (intramolecular) or from multiple DNA-strands (intermolecular), but studies on their biological functions have been often limited to intramolecular G4s, owing to the low probability of intermolecular G4s to form within genomic DNA. Herein, we report that the endogenous protein Cockayne Syndrome...

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Literature Corpus work: 9556fcfd-ad61-5c28-a059-8458c58b749a
DOI: 10.1101/2021.03.25.436565

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