Article

Dominant Formation of DNA:RNA Hybrid G-Quadruplexes in the Genomes of Living Human and Mouse Cells

2024-12-28

Abstract excerpt

Guanine-rich nucleic acids can form four-stranded structures known as G-quadruplexes (G4s), which play critical roles in essential cellular activities. Putative G-quadruplex-forming sequences (PQSs) are abundant in the genomes of animal cells. To date, research on G4s has focused primarily on intramolecular G4s formed by four contiguous G-tracts from the same nucleic acid strand. However, our recent study indicate...

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Literature Corpus work: fdb4786f-4ecd-574f-ba30-d4c3981fda2e
DOI: 10.1101/2024.12.27.630557

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