Article

G4 Biology and Scope for Potential Therapeutic Intervention against Multiple Disease Adversaries

2024-09-17

Abstract excerpt

DNA - the repository of genetic information harbours sequences rich in Guanine that adopt non-B form four-stranded DNA secondary structures termed as G-quadruplexes (G4s). Such non-canonical structures tend to impede the progression of routine replisome and are implicated to have crucial roles in replication, transcription and epigenetic regulation while also ensuring genomic stability. It is now fully established...

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Literature Corpus work: 22e5438a-d357-587b-8f1c-3eac5552eff3
DOI: 10.20944/preprints202409.1191.v1

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