Article

Genome-wide hyper-mutated genes and hotspot detection across 27 cancers

2026-05-13

Abstract excerpt

<title>Abstract</title> <p> Background Somatic genetic alterations across different types of tumors are key to understand pan-cancer etiology. Although, pan-cancer genomics analyses have been conducted extensively, the contribution of mutation burden and hotspots is less characterized. Results In this study, we analyzed the somatic variant burden in 10,008 tumor samples spanning 27 cancer types, leveraging dat...

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Literature Corpus work: 9531ccdc-6f1c-5869-9bf6-e07afae0503a
DOI: 10.21203/rs.3.rs-9516616/v1

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