Article

SCRIPT: predicting single-cell long-range <i>cis</i> -regulation based on pretrained graph attention networks

2025-04-30

Abstract excerpt

Single-cell cis -regulatory relationships (CRRs) are essential for deciphering transcriptional regulation and understanding the pathogenic mechanisms of disease-associated non-coding variants. Existing computational methods struggle to accurately predict single-cell CRRs due to inadequately integrating causal biological principles and large-scale single-cell data. Here, we present SCRIPT (Single-cell Cis -regula...

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Literature Corpus work: 7512da90-6111-5df9-b3c7-99ea63132ea4
DOI: 10.1101/2025.04.27.650894

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