Article

A pathogenic subpopulation of human glioma associated macrophages linked to glioma progression

2025-02-17

Abstract excerpt

<h4>Summary</h4> Malignant gliomas follow two distinct natural histories: de novo high grade tumors such as glioblastoma, or lower grade tumors with a propensity to transform into high grade disease. Despite differences in tumor genotype, both entities converge on a common histologically aggressive phenotype, and the basis for this progression is unknown. Glioma associated macrophages (GAM) have been implicated...

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Literature Corpus work: 9508e833-02cc-5aa8-a773-58fe85d8cb38
DOI: 10.1101/2025.02.12.637857

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