Article

The genetic and phenotypic correlates of neonatal Complement Component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders

2022-11-15

Abstract excerpt

The complement system, including complement components 3 and 4 (C3, C4), traditionally has been linked to innate immunity. More recently, complement components have also been implicated in brain development and the risk of schizophrenia. Based on a large, population-based case-cohort study, we measured the blood concentrations of C3 and C4 in 68,768 neonates. We found a strong correlation between the concentration...

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Literature Corpus work: 9490bae5-8024-52e8-965e-0bfe14b41c58
DOI: 10.1101/2022.11.09.22281216

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