Article

The complement system supports normal postnatal development and gonadal function in both sexes

2017-12-13

Abstract excerpt

Male and female infertility are clinically managed and classified as distinct diseases, and relatively little is known about mechanisms of gonadal function common to both sexes. We used genome-wide genetic analysis on 74,896 women and men to find rare genetic variants that modulate gonadal function in both sexes. This uncovered an association with variants disrupting CSMD1 , a complement regulatory protein locate...

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Literature Corpus work: 81c8b04d-fb21-5b80-b49d-65958f35379f
DOI: 10.1101/233825

Open publication

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